Treatment Of Lung Hypertension Does Not Help Patients With Chronic Bronchitis
�Patients with chronic smoker's bronchitis often suffer from increased
air pressure in the blood vessels supplying the lung (pulmonic
hypertension). The blood pressure increases farther during exercise
and tooshie lead to severe limitation of physical activity.
In patients with other diseases causation pulmonary hypertension, for
representative rheumatic or heart conditions, drug therapy has been shown
to improve practice capacity and decrease mortality.
Daiana Stolz (University Hospital Basel, Switzerland) and her
colleagues precious to find out whether patients with severe chronic
bronchitis as well benefit from treatment of pulmonary high blood pressure.
They compared the effect of the lung vasodilator bosentan, a standard
therapy for pulmonary hypertension, with the effect of placebo in 30
patients with severe chronic bronchitis.
All patients underwent respective tests including lung function and
computed tomography in front and afterwards the three months of therapy.
The study shows that, in contrast to patients with other causes of
pulmonic hypertension, chronic bronchitis patients do non improve
their exercise mental ability if treated with bosentan.
This study besides suggests that the treatment of pneumonic hypertension
in patients with chronic bronchitis reduces the amount of oxygen in
the profligate. "Although we hoped to alleviate shortness of breath by treating
patients this way, we could non identify any benefit of the therapy,"
said Daiana Stolz.
Title Of The Original Article
A randomised, controlled trial of bosentan in severe COPD
The European Respiratory Journal is the peer-reviewed scientific publication of the European Respiratory Society (more than 8,000 specialists in lung diseases and respiratory medical specialty in Europe, the
United States and Australia).
European Respiratory Journal
The European Respiratory Society (ERS)
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posted by spaulettasanramon @ 21:29
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